A Method


The present disclosure teaches a method for producing a cyclic peptide in a plant. The term "cyclic peptide" includes but is not limited to a cyclotide. The cyclic peptide may be naturally cyclical or may be a naturally linear peptide rendered cyclic in the plant. In an embodiment, the cyclic peptide is extracted from the plant for use in a variety of applications including pharmacological such as the treatment of cancer, cardiovascular disease, infectious disease, immune diseases and pain. In another embodiment, the cyclic peptide protects the plant or parts of the plant from pathogen infection or infestation.


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