Induced Neural Stem Cells


The present invention relates to a method of deriving an induced neural stem cell (iNCS) by nuclear reprogramming of a somatic cell, wherein the method comprises a step of contacting the somatic cell with Oct4 protein or a functionally equivalent analogue, variant or fragment thereof for a limited time period, as well as an induced neural stem cell obtained by this method.

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Document History
  • Publication: Sep 26, 2013
  • Application: Feb 27, 2013
    WO EP 2013000573 W
  • Priority: Mar 21, 2012
    EP EP 12001981 A

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