Inhibitor Of Trpm-4 Ion Channel For Treating Or Preventing Neurodegeneration

Abstract

The invention relates to a compound which is effective in inhibiting the function of the TRPM4 ion channel and the use of such compound in treating or preventing a neurodegenerative disease, such as Multiple Sclerosis, Parkinson's disease, Alzheimer's disease, or a myotrophic lateral sclerosis, in a subject. The invention also provides a pharmaceutical composition comprising a TRPM4 inhibitory compound. The invention further relates to in vitro methods for identifying pharmaceutically active compounds that are useful for treating or preventing a neurodegenerative disease.


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Document History
  • Publication: Jul 4, 2013
  • Application: Dec 21, 2012
    WO EP 2012076773 W
  • Priority: Dec 29, 2011
    EP EP 11196121 A

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