Compounds For Use In Boosting Coagulation


The present invention relates to inhibitors of antithrombin III and the medical use thereof in treating or preventing bleeding. The inhibitors are preferably used in subjects suffering from an acquired or genetic bleeding disorder, such as haemophilia, or in a subjects having a clinical condition characterised by excessive bleeding, such as surgery, trauma and internal bleeding. The inhibitor of antithrombin III can e.g. a peptide, an aptamer or an antibody or antibody fragment that specifically binds to and inhibits antithrombin III.

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Document History
  • Publication: Feb 28, 2013
  • Application: Aug 24, 2012
    WO NL 2012050581 W
  • Priority: Aug 25, 2011
    US US 201161527140 P

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