Activity Based Probes (abps) Interacting With Glycosidases

Abstract

An activity based probe (ABP) comprising a glycosidase inhibitor, and a detection-group. The ABPs of the inventions are used for diagnosing storage disorder for screening of compounds suitable for preventing and/or treating a storage disorder, for monitoring of therapeutic enzymes for lysosomal storage disorders, and for ultra- sensitive visualization of glycosidase-fusion proteins in molecular imaging.


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