Treatment Of Suicidal Ideation Or Behavior Using Inhibitors Of Nicotinic Acetylcholine Receptors


The invention concerns methods of treating suicidal ideation or behavior in a subject in need thereof, comprising decreasing endogenous nicotinic acetylcholine receptor (nAChR) activity in the subject; therapeutic packages for treating suicidal ideation or behavior; and methods for determining the efficacy of a treatment for suicidal ideation or behavior. In some embodiments, the treatment methods comprise administering to the subject an effective amount of an inhibitor of a nAChR, such as a lithium compound, mecamylamine, clozapine, or asenapine.


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Document History
  • Publication: Aug 18, 2011
  • Application: Oct 15, 2010
    WO US 2010/0052949 W
  • Priority: Oct 16, 2009
    US US 25234309 P

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