Compositions Containing Berberine Or Analogs Thereof For Treating Rosacea Or Red Face Related Skin Disorders


The present invention discloses topical pharmaceutical formulations of berberine and its biologically equivalent analogues, such as palmatine and coptisine, for the treatment of rosacea and other red face-related skin disorders. The topical pharmaceutical formulations of this invention contain purified berberine as the primary active drug ingredient at concentrations higher than 0.1%. The invention also discloses methods of treating rosacea and other red face related skin disorders, such as steroid-induced rosacea-like dermatitis, comprising the administration of topical pharmaceutical formulations that contain berberine or its biologically equivalent analogues, such as palmatine.

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Document History
  • Publication: Jan 6, 2011
  • Application: Jun 30, 2010
    WO CN 2010000983 W
  • Priority: Jun 30, 2009
    US US 22172509 P

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