Methods For Detecting And Modulating The Sensitivity Of Tumour Cells To Anti-mitotic Agents

Abstract

A method of screening a tumour cell for resistance to a tubulin-binding agent, the method comprising detecting the expression of any one or more of class II, class III and class IVb ß-tubulin by the tumour cell, wherein the expression of any one or more of class II, class III and class IVb ß-tubulin indicates that the tumour cell has resistance or potential resistance to the tubulin-binding agent.


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Document History
  • Publication: Sep 12, 2008
  • Application: Mar 5, 2008
    WO AU 2008/000298 W
  • Priority: Sep 28, 2007
    AU AU 2007/905307 A
  • Priority: Mar 5, 2007
    AU AU 2007/901131 A

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