Novel 4-amino-quinoline Derivatives Useful As Anti-malaria Drugs


The present invention relates to clotrimazole/quinoline hybrids useful as active ingredients of anti-malaria drugs. The compounds show a remarkable in vitro biological activity especially against the chloroquine-resistant Plasmodium falciparum strains and in vivoactivity against P.berghei.

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Document History
  • Publication: Aug 28, 2008
  • Application: Feb 18, 2008
    WO EP 2008051923 W
  • Priority: Feb 21, 2007
    US US 89086207 P
  • Priority: Feb 20, 2007
    DK DK PA200700263 A

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