Stabilized Picoplatin Oral Dosage Form

  • Published: Aug 14, 2008
  • Earliest Priority: Feb 09 2007
  • Family: 14
  • Cited Works: 1
  • Cited by: 1
  • Cites: 9
  • Additional Info: Full text
Abstract

The invention provides an oral dosage form for the anti-cancer drug picoplatin comprising a core and a coating, the dosage form being free of redox-active metal salts. The core of the tablet is a substantially dry powder comprising about 10 to 60 wt% picoplatin wherein the picoplatin is a particulate of less than about 10 microns average particle diameter, about 40-80 wt% of a filler comprising a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate, and an effective amount of up to about 5 wt% of a lubricant. The dosage form can further include a dispersant.


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Document History
  • Publication: Aug 14, 2008
  • Application: Feb 8, 2008
    WO US 2008/0001752 W
  • Priority: Feb 13, 2007
    US US 88968107 P
  • Priority: Feb 9, 2007
    US US 88917107 P

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