Method For Induction/differentiation Into Photoreceptor Cell

Abstract

Disclosed is a method for the production of a retinal progenitor cell of a primate, which comprises the steps of: culturing an embryonic stem cell from a primate in a serum-free culture medium in the form of a floating aggregate; and collecting the retinal progenitor cell from the culture. Also disclosed is a method for the production of a photoreceptor progenitor cell, which comprises the steps of: culturing an isolated retinal progenitor cell (which has been differentiated and induced from an embryonic stem cell) in the presence of a gamma-secretase inhibitor under adhesive culture conditions; and collecting the retinal progenitor cell from the culture.


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Document History
  • Publication: Jul 24, 2008
  • Application: Jan 11, 2008
    WO JP 2008050305 W
  • Priority: Jan 18, 2007
    JP 2007009617 A

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