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Polymorphisms Predictive Of Platinum-coordinating Complex-induced Ototoxicity

Abstract

Provided are methods, nucleic acids, and arrays for assessing the susceptibility of a subject to the development of ototoxicity in response to receiving one or more platinum-coordinating compounds, the method including determining the presence or absence of one or more polymorphisms, wherein the presence or absence of one or more such polymorphisms is indicative of susceptibility to the development of ototoxicity.


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Document History
  • Publication: May 22, 2008
  • Application: Nov 15, 2007
    WO CA 2007002067 W
  • Priority: Sep 14, 2007
    US US 96008907 P
  • Priority: Nov 15, 2006
    US US 85892506 P

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