Abstract

The present invention relates to a new class of terpene-derived compounds having an antibiotic activity and of the formulae (I) or (II) in which A is selected from NR<SUB>1</SUB>, O, S, CR<SUB>2</SUB>R<SUB>3</SUB> or R-(CH<SUB>2</SUB>)<SUB>n</SUB>-R', wherein R and R' represent independently NH, O, S or CH<SUB>2</SUB>, and in which R<SUB>1</SUB>, R<SUB>2</SUB> et R<SUB>3</SUB> are substituents and n is higher than or equal to 1, in particular equal to 2. The invention relates to the compound according to both the formula (I) or the formula (II) taken individually, to mixtures of the two compounds, and to compositions, mainly therapeutic ones, comprising at least one of the compounds or said mixture. According to a particular embodiment, the compound ((I) or (II) taken individually, the mixtures of both compounds and the compositions of the invention are used in the treatment of difficult C-related digestive infections. In one particular embodiment, the compound of the formula (I) is margaucine, a compound produced by a bacterial stem.


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Document History
  • Publication: Apr 3, 2008
  • Application: Sep 21, 2007
    WO FR 2007001544 W
  • Priority: Mar 30, 2007
    FR FR 0702357 A
  • Priority: Sep 22, 2006
    FR FR 0608345 A

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