Specific Therapy Using Integrin Ligands For Treating Cancer


The invention relates to a combination therapy for the treatment of tumors and tumor metastases comprising administration of integrin ligands, preferably integrin antagonists, together with co-therapeutic agents or therapy forms that have synergistic efficacy when administered consecutively with said ligands, such as chemotherapeutic agents and or radiation therapy. The therapy results in a synergistic potential increase of the inhibition effect of each individual therapeutic on tumor cell proliferation, yielding more effective treatment than found by administering an individual component alone, concurrently or not in the dosage regime of the present invention.

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Document History
  • Publication: Jul 26, 2007
  • Application: Jan 18, 2007
    WO US 2007/0001446 W
  • Priority: Jul 31, 2006
    EP EP 06015883 A
  • Priority: Jan 20, 2006
    EP EP 06006003 A
  • Priority: Jan 18, 2006
    EP EP 06000988 A
  • Priority: Jan 18, 2006
    EP EP 06001044 A

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