Cell, Method And Kit For Conducting An Assay For Neutralizing Antibodies

Abstract

The present invention provides a cell for use in a one-step cell-based assay for an extracellular ligand (e.g., IFNα) that initiates a ligand-specific signal at the nucleus of the cell and for neutralizing antibodies against the extracellular ligand. The cell-based one-step assay allows both the extracellular ligand concentration and the neutralizing antibody titer to be quantified in a single sample (e.g., serum) without the need for sample dilution and addition of exogenous extracellular ligand.


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Document History
  • Publication: May 15, 2018
  • Application: Mar 4, 2009
    US US 92111009 A
  • Priority: Mar 4, 2009
    US US 92111009 A
  • Priority: Mar 4, 2009
    US US 2009/0036044 W
  • Priority: Mar 4, 2008
    US US 3362108 P

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