2,5,6,7-tetrasubstituted Thiazolo[4,5-b]Pyridine Derivatives And Use Thereof

  • Published: Apr 3, 2018
  • Earliest Priority: Apr 29 2014
  • Family: 4
  • Cited Works: 17
  • Cited by: 0
  • Cites: 2
  • Additional Info: Cited Works Full text
Abstract

As investigating an anti-sepsis effect through a CLP-induced sepsis animal test that a sepsis survival rate is increased, it is identified that the pharmaceutical composition contains the 2,5,6,7-tetrasubstituted thiazolo[4,5-b]pyridine derivative or a pharmaceutically available salt thereof as an active ingredient to be used as a therapeutic agent for a vascular inflammatory disease and infectious disease including sepsis triggered by activity of HMGB1 protein.


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Document History
  • Publication: Apr 3, 2018
  • Application: Apr 28, 2015
    US US 201514698073 A
  • Priority: Apr 29, 2014
    KR KR 20140051964 A

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