Kinase Inhibitor And Use Thereof

Abstract

The invention relates to a CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers; a pharmaceutical formulation, pharmaceutical composition and kit comprising said CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers, and use of said CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers. For example, the compounds of the invention are useful for reducing or inhibiting the activity of CDK4/6 kinase in a cell, and/or treating and/or preventing a cancer-related disease mediated by CDK4/6 kinase.


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Document History
  • Publication: Oct 24, 2017
  • Application: Dec 30, 2014
    US US 201415108903 A
  • Priority: Dec 30, 2014
    CN CN 2014095615 W
  • Priority: Dec 31, 2013
    CN CN 201310749417 A

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