{"search_session":{},"preferences":{"l":"zh","queryLanguage":"zh"},"patentId":"US_9701723_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"170-989-565-201-267"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11620,"type":"PATENT","title":"Icahn School of Medicine at Mount Sinai - Patent Portfoilo","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3154,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8295,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: Icalh* medici*
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Select all patents in the collection and expand by simple families. Add to collection. Total patents: 896
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
Search Applicants and Owners separately: Icalh* medici*
Select more for logical variants. Add to collection.
Select all patents in the collection and expand by simple families. Add to collection. Total patents: 896
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
R-I-Q-D-L-E-K-Y-V-E-D-T-K-I-D-L-W-S-Y-N-A-E-L-L-V-A-L-E-N-Q-H-T-I-D-L-T-D-S-E-M-N-K-L-F-E-X1T-X2-X3-Q-L-R-E-N-A (SEQ ID NO: 15), wherein X1, X2, and X3 are hydrophilic, basic amino acids."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide comprises SEQ ID NO: 16, SEQ ID NO: 17, or SEQ ID NO: 18."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide selectively binds neutralizing antiserum capable of binding an influenza hemagglutinin."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide is further (a) acetylated at its N-terminus; or (b) linked to polyethylene glycol at its N- and/or C-terminus."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide is further linked to a carrier protein."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide has the amino acid sequence RIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENA (SEQ ID NO: 2), and wherein the immunogenic core polypeptide is linked at its C-terminus to a polypeptide having the amino acid sequence DYKDDDDKC (SEQ ID NO: 63)."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein X1 is K or R, X2 is K or R, and X3 is K or R."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to one or more tags."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 7, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to one or more tags."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to a T cell epitope."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 7, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to a T cell epitope."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to a Toll Like Receptor ligand."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 7, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to a Toll Like Receptor ligand."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 1, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to a T4 foldon domain or a fragment thereof."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The immunogenic composition of claim 7, wherein the immunogenic core polypeptide is directly or indirectly linked at its N- and/or C-terminus to a T4 foldon domain or a fragment thereof."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["A method of inducing an immune response to an influenza virus in a subject, comprising administering to the subject an effective amount of the immunogenic composition of claim 1."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["A method of inducing an immune response to an influenza virus in a subject, comprising administering to the subject an effective amount of the immunogenic composition of claim 7."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["A method of preventing an influenza virus disease in a subject, comprising administering to the subject an effective amount of the immunogenic composition of claim 1."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["A method of preventing an influenza virus disease in a subject, comprising administering to the subject an effective amount of the immunogenic composition of claim 7."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 16, wherein the subject is a human."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 17, wherein the subject is a human."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 18, wherein the subject is a human."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 19, wherein the subject is a human."],"number":23,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}