{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_9416103_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"146-458-512-870-990","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11844,"type":"PATENT","title":"University of Kansas Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":8584,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8456,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: univ* AND Kansas. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1781
Search Applicants and Owners separately:Univ* Arkansas. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2874
Search Applicants and Owners separately: univ* AND Kansas. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1781
Search Applicants and Owners separately:Univ* Arkansas. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2874
wherein R1 is 5-O-methyl, 7-O-methyl, or 7-OH;\n
R2 is C1-C6 linear alkyl;\n
and R3 is"],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein the R2 is n-butyl."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein R1 is 7-O-methyl."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein R3 is"],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein the compound has a KD for CB1R and CB2R of less than 1 micromolar."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 5 wherein the compound has a KD for CB1R and CB2R of less than 100 nM."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein the compound is a neutral CB1R antagonist."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein the compound is a CB2R agonist."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein the compound is TV-5-249 or TV-6-41."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 wherein the composition is a pharmaceutical composition."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 10 wherein the pharmaceutical composition is a sterile solution for injection."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 10 wherein the pharmaceutical composition is tablet, capsule, gel cap, or pill for oral administration."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 10 wherein the pharmaceutical composition is a unit dosage composition for treating alcoholism or drug abuse in a human."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["A method of treating alcohol or drug abuse in a human comprising:\n
administering a compound of formula III in an amount and for a time effective to treat alcohol or drug abuse in a human in need thereof:\n\n
wherein R1 is 5-O-methyl, 7-O-methyl, or 7-OH;\n
R2 is C1-C6 linear alkyl;\n
and R3 is"],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 14 wherein the compound is TV-5-249 or TV-6-41."],"number":15,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}