The present invention concerns methods and compositions involving inhibitors of Pre-B Cell Colony Enhancing Factor (PBEF) for inflammatory conditions and diseases, including acute lung injury (ALI), ventilator-induced lung injury (VILI), and acute respiratory distress syndrome (ARDS). The present invention also concerns biomarkers for inflammation as well as methods for screening for PBEF inhibitors.

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Document History
  • Publication: Aug 9, 2016
  • Application: Jul 23, 2010
    US US 84277310 A
  • Priority: Jul 23, 2010
    US US 84277310 A
  • Priority: Jul 23, 2009
    US US 22787809 P

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