{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_9314484_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"089-954-487-909-490","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11620,"type":"PATENT","title":"Icahn School of Medicine at Mount Sinai - Patent Portfoilo","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3154,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8295,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: Icalh* medici*
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Select all patents in the collection and expand by simple families. Add to collection. Total patents: 896
Search Applicants and Owners separately: Icalh* medici*
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Select all patents in the collection and expand by simple families. Add to collection. Total patents: 896
a flagellin or fragment thereof and a tumor-associated antigen (TAA),\n
wherein the flagellin or fragment thereof is capable of binding to one or more of Toll-like receptor-5 (TLR5), Naip5 or Ipaf."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["A method for treating a cancer in a patient in need of such treatment comprising administering to said patient the composition of claim 1 in an effective amount for eliciting an anti-tumor immune response."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["A method for treating a cancer in a patient in need of such treatment comprising administering to said patient a composition comprising a tumor cell expressing a fusion protein, wherein said fusion protein comprises:\n
a flagellin or fragment thereof and a tumor associated antigen (TAA), in an effective amount for eliciting an anti-tumor immune response,\n
wherein the flagellin or fragment thereof is capable of binding to one or more of Toll-like receptor-5 (TLR5), Naip5 or Ipaf."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein said DC has phagocytosed said tumor cell."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 3, wherein said patient is a human."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein said tumor cell is an autologous cell."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein said DC is an autologous cell."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein said tumor cell is lethally irradiated."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein said patient is a human."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 3, wherein said tumor cell is an autologous cell."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 3, wherein said tumor cell is lethally irradiated."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the flagellin comprises an amino acid sequence substantially identical to an amino acid sequence selected from the group consisting of SEQ NOs: 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20, or a fragment thereof."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the flagellin fragment comprises and an amino acid sequence at least 80% identical to the amino acid sequence of SEQ ID NO: 31 or SEQ ID NO: 32."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 3, wherein the flagellin comprises an amino acid sequence substantially identical to an amino acid sequence selected from the group consisting of SEQ NOs: 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20, or a fragment thereof."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 3, wherein the flagellin fragment comprises and an amino acid sequence at least 80% identical to the amino acid sequence of SEQ ID NO: 31 or SEQ ID NO: 32."],"number":15,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}