2,3-fluorinated Glycosides As Neuraminidase Inhibitors And Their Use As Anti-virals

Abstract

Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The therapeutic effect is achieved via inhibition of viral neuraminidases, also known as viral sialidases. These neuraminidases are classified under the GH34 family of viral enzymes.


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Document History
  • Publication: Aug 26, 2014
  • Application: Jul 15, 2010
    US US 201013382284 A
  • Priority: Jul 15, 2010
    US US 201013382284 A
  • Priority: Jul 15, 2010
    CA CA 2010001063 W
  • Priority: Jul 15, 2009
    US US 21378609 P

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