{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_8741351_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"100-006-045-389-359"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11797,"type":"PATENT","title":"Queen's University at Kingston Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":5666,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8427,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: queen* AND univ*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1261
Search Applicants and Owners separately: queen* AND univ*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1261
a substantially spherical and biocompatible copolymer of sodium acrylate and vinyl alcohol, and\n
doxorubicin."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 1, wherein the doxorubicin is associated with the copolymer by an ionic interaction."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 1, wherein the microsphere is swellable."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 1, wherein the doxorubicin is contained within the microsphere."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 1, wherein the doxorubicin is adsorbed or absorbed by the microsphere."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 1, wherein the diameter of the microsphere ranges from about 10 μm to about 2000 μm."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 3, wherein the diameter of the microsphere ranges from about 10 μm to about 400 μm before swelling."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 3, wherein the diameter of the microsphere ranges from about 10 μm to about 2000 μm after swelling."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["An injectable composition comprising the microsphere of claim 1 and a biocompatible carrier, wherein the composition is sterile."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 9, wherein the composition comprises the microsphere in an amount from about 10% to about 50% by weight and the biocompatible carrier in an amount from about 50% to about 90% by weight."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 9, wherein the biocompatible carrier comprises a salt composed of cations selected from the group consisting of sodium, potassium, calcium, magnesium, iron, zinc, ammonium, and mixtures thereof, in an amount of from about 0.01 M to about 5 M."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 9, further comprising a fluorescent marker, chemical dye, contrast agent, magnetic resonance imaging agent, or a mixture thereof."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 9 where the composition is injectable through a needle of about 18 gauge or smaller."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["A microsphere suitable for active embolization, comprising:\n
a substantially spherical and swellable, biocompatible anionic copolymer of sodium acrylate and vinyl alcohol, and\n
doxorubicin."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 14, wherein the doxorubicin is associated with the copolymer by an ionic interaction."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The microsphere of claim 14, wherein the diameter of the microsphere ranges from about 10 μm to about 2000 μm."],"number":16,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}