Doc Type: Granted Patent

Method Of Modulation Of Expression Of Epidermal Growth Factor Receptor(egfr) Involving Mirna

Abstract

The present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) and its downstream signalling effectors. In particular, the present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) or like molecule in a cell comprising contacting said cell with an agent capable of directly or indirectly interacting with the 3'-untranslated region (UTR) of the mRNA of said EGFR or like molecule, wherein the UTR is encoded by a sequence which comprises a sequence having at least about 70% identity with at least one sequence selected from the group consisting of the sequences set forth in SEQ ID NOs: 1-36.


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Document History
  • Publication: Mar 18, 2014
  • Application: Aug 28, 2007
    US US 31050907 A
  • Priority: Aug 28, 2007
    AU AU 2007/001247 W
  • Priority: Feb 6, 2007
    AU AU 2007/900558 A
  • Priority: Aug 28, 2006
    AU AU 2006/904662 A

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