The present invention provides novel cell-based and animal-based assays for determining antagonists of PKCepsilon and uses of the isolated antagonist compounds for modulating insulin clearance and secretion. The invention also provides novel animals and cells such as animals and cells suitable for use in the assays.

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Document History
  • Publication: Dec 3, 2013
  • Application: Sep 16, 2004
    US US 57211004 A
  • Priority: Sep 16, 2004
    AU AU 2004/001255 W
  • Priority: Jul 22, 2004
    AU AU 2004/904077 A
  • Priority: Sep 16, 2003
    AU AU 2003/905421 A

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