{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_8283126_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"066-651-001-808-364","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10709,"type":"PATENT","title":"Rockefeller University Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":4213,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8226,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: \"Rockefeller University\"; \"Univ* Rockefeller\"; \"Univ* Rockef*\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4020
Search Applicants and Owners separately: \"Rockefeller University\"; \"Univ* Rockefeller\"; \"Univ* Rockef*\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4020
providing a screening protein consisting essentially of a sodium ion channel voltage sensor domain having transmembrane segments S1-S4 of the ion channel protein;\n
contacting the screening protein with a chemical compound;\n
determining whether the chemical compound binds to the screening protein;\n
wherein chemical compounds that bind to the screening protein are drug candidates."],"number":16,"annotation":false,"claim":true,"title":false},{"lines":["A method according to claim 16, wherein the screening protein is immobilized on a solid support."],"number":17,"annotation":false,"claim":true,"title":false},{"lines":["A method according to claim 16, wherein the chemical compound is immobilized on a solid support."],"number":18,"annotation":false,"claim":true,"title":false},{"lines":["A method according to claim 16, wherein the chemical compound is a biological molecule."],"number":19,"annotation":false,"claim":true,"title":false},{"lines":["A method according to claim 19, wherein the biological molecule is a polyamino acid."],"number":20,"annotation":false,"claim":true,"title":false},{"lines":["A method according to claim 16, wherein the chemical compound is a small molecule."],"number":21,"annotation":false,"claim":true,"title":false},{"lines":["A method according to claim 16, wherein the drug candidate alters the target voltage dependent ion channel proteins."],"number":22,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}