{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_7867716_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"044-451-052-611-161","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10839,"type":"PATENT","title":"Texas A&M University System - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":5182,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8288,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: Texas AND A&M AND Univ*; A&M AND Univ*
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4521
Search Applicants and Owners separately: Texas AND A&M AND Univ*; A&M AND Univ*
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4521
disposing operably one or more protein pores in a divider between a first and a second chamber exposing said one or more protein pores to a solution suspected of comprising one or more analytes at a temperature at or above 55° C.; and\n
detecting a current between the first and a second chambers with a current detector when the one or more protein pores are exposed to a solution suspected of comprising the one or more analytes at a temperature at or above 55° C., wherein each of the one or more protein pores comprise\n
at least one high temperature stabilization molecular adapter that stabilizes the one or more protein pores at a temperature at or above 55° C. and the one or more analytes produces a change in current between the first and a second chambers detectable by the current detector."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the one or more protein pores are engineered protein pores."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein one or more of the one or more protein pores is an αHL pore."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the solution is a pH buffered KCl solution."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the one or more analytes comprise an environmental toxin."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the one or more analytes comprise a chemical weapon."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the one or more analytes comprise a pharmaceutical."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the one or more analytes comprise an arsenical."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the solution comprises an ionic solution suspected of comprising one or more chemically distinct analytes capable of bonding with the one or more protein pores."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the current detector is capable of stochastic sensing."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the change in current comprises a change in the magnitude of the current."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the at least one high temperature stabilization molecular adaptor comprises β-cyclodextrin (βCD)."],"number":12,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}