Activation Induced Deaminase (aid)

Abstract

The present invention identifies that the expression of Activation Induced Deaminase (AID) or its homologues in cells confers a mutator phenotype and thus provides a method for generating diversity in a gene or gene product as well as cell lines capable of generating diversity in defined gene products. The invention also provides methods of modulating a mutator phenotype by modulating AID expression or activity.


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Document History
  • Publication: Oct 26, 2010
  • Application: Nov 10, 2004
    US US 98532104 A
  • Priority: May 9, 2003
    GB GB 0302002 W
  • Priority: Jul 29, 2002
    GB GB 0217519 A
  • Priority: Jun 14, 2002
    GB GB 0213751 A
  • Priority: May 10, 2002
    GB GB 0210755 A

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