{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_7803351_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"075-333-179-965-052"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8904,"type":"PATENT","title":"Univ Washington Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":15386,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8219,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
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Search applicants and owners= \"Univ Washington', \"Washington Univ\", \"University of Washington\", \" Washington University\", \"Univ Washington NOT state\", \" Univ Washington NOT state NOT George\".
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a blood brain barrier (BBB)-permeant, Aβ-targeting peptide comprising an amino acid sequence of SEQ ID NO: 1; and\n
a chelation core;\n
wherein the Aβ-targeting peptide is coupled to the chelation core."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["A compound in accordance with claim 1 wherein said chelation core comprises a medical imaging agent."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["A compound in accordance with claim 1 wherein said chelation core has the structure of Formula I:\n
wherein X is one of technetium-99m, technetium 94m and rhenium."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["A compound in accordance with claim 1 wherein said chelation core has a structure selected from the group consisting of:\n
Formula I, wherein X is one of technetium-99m, technetium 94m and rhenium;\n\n
Formula II, wherein X is one of technetium-99m, technetium 94m and rhenium;\n\n
Formula III, wherein X is one of technetium-99m, technetium 94m and rhenium;\n
and\n\n
Formula IV, wherein X is one of technetium-99m, technetium-94m and rhenium."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition for imaging amyloid deposits, comprising:\n
the compound in accordance with claim 1;\n
a medical imaging agent selected from the group consisting of a radionuclide, a relaxivity metal, a fluorochrome, a dye, and an enzyme substrate, and\n
a pharmaceutically acceptable excipient or diluent;\n
wherein the medical imaging agent is coupled to said chelation core."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition in accordance with claim 5 wherein said medical imaging agent comprises a radioisotope."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition in accordance with claim 5 wherein said medical imaging agent comprises technetium-99m."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition in accordance with claim 5 wherein said medical imaging agent comprises technetium-94m."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition in accordance with claim 5, comprising a radionuclide or a relaxivity metal, said radionuclide or relaxivity metal coordinated to said chelation core."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition in accordance with claim 9, wherein said chelation core is selected from the group consisting of DTPA, EDTA, DOTA, TETA and ε-KGC amide."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition in accordance with claim 9, comprising a radionuclide wherein said radionuclide is a radioactive isotope of a metal selected from the group consisting, of: Tc, Ru, In, Ga, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb, Cu, and Ta."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["A diagnostic composition in accordance with claim 9, comprising a relaxivity metal wherein said relaxivity metal is a paramagnetic isotope of a metal selected from the group consisting of Mn, Cr, Fe, Gd, Eu, Dy, Ho, Cu, Co, Ni, Sm, Tb, Er, Tm, and Yb."],"number":12,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}