{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_7786310_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"119-586-384-347-886","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8901,"type":"PATENT","title":"University of Michigan Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":14369,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8216,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners= \"Univ Michigan\", \" Michigan Univ\", \" Univ Michigan NOT state NOT tech NOT Eastern\", \"Univ Michigan NOT technological\", \" Univ Michigan NOT Western\"
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Total patent : 14104
Search Applicants and Owners= \"Univ Michigan\", \" Michigan Univ\", \" Univ Michigan NOT state NOT tech NOT Eastern\", \"Univ Michigan NOT technological\", \" Univ Michigan NOT Western\"
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Total patent : 14104
wherein R1 is a phenyl or CO2H, wherein R2 is an allyl,\n\n
and wherein R3 is OH ."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1 , wherein said activation domain is selected from the group consisting of:"],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1, wherein said isoxazolidine is oligomerized."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1, wherein said activation domain is fused to a DNA binding domain."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 4, wherein said DNA binding domain is specific for a promoter region in a gene."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 5, wherein said gene is selected from the group consisting of: abl, Bcl-2, Bcl-xL, erb, fms, gsp, hst, jun, myc, neu, raf, ras, ret, src, trk, BRCA1, BRCA2, C-CAM, p16, p21, p53, p73, Rb, p27, KDR, Renin, C-raf, NOS, NOS(I), ERK7, MAPK, Fms-TK, PKC-α, PKC-α1, PKC-β, SAPK-α, CDK2, Chp-JNK, Ha-ras, C-fos, bc1-2, NF-κB, Cyclin-E AP-1, c-Fos, c-Jun, NF-E2, CRE-BP1, ATF, CREB, C/EBP, NF-IL6, MyoD, E2F, USF, NF-1, RF-X, CP1, ER, GR, PR, RAR, RXR, T3R, COUP, GATA-1, Sp1, YY1, GAL4, EN, HNF-1, OCT, HNF-3, c-Myb, Ets, IRF-1, G3PDH, N/K ATPase, Ca-ATPase, IL-1β, IL-5, IL-6, IL-4, IFN-γ, MIP-1α, MIP-2, MCP-1, RANTES, TNF-α, TNF-αR1, TGF- β, and TGF-βR1."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 1, wherein said activation domain is coupled to a compound, wherein said compound is one of a plurality of compounds of a compound library."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The composition of claim 7, wherein said compound library comprises putative ligands selected from the group consisting of carbohydrates, monosaccharides, oligosaccharides, polysaccharides, amino acids, peptides, oligopeptides, polypeptides, proteins, nucleosides, nucleotides, oligonucleotides, polynucleotides, lipids, retinoids, steroids, glycopeptides, glycoproteins, proteoglycans, and synthetic small molecule organic compounds."],"number":8,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}