Mdr1 Variants And Methods For Their Use

Abstract

This invention provides the identification of a truncation polymorphism of the mdr1 gene that is linked to ivermectin sensitivity in subjects, such as collies. Also provided are methods for detecting drug transport sensitivity in a subject, and animal models and in vitro cell systems using cells from animals having an mdr1 truncation.


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Document History
  • Publication: Aug 17, 2010
  • Application: Apr 28, 2008
    US US 11097208 A
  • Priority: Apr 28, 2008
    US US 11097208 A
  • Priority: Jul 21, 2004
    US US 89643404 A
  • Priority: Jan 10, 2002
    US US 4467102 A
  • Priority: Aug 24, 2001
    US US 31482901 P
  • Priority: Jan 12, 2001
    US US 26157801 P

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