Disease Model Incorporation Into An Artificial Immune System (ais)


The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising a three-dimensional matrix comprising lymphoid tissue, a three-dimensional matrix comprising epithelial and/or endothelial cells, and diseased cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.

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Document History
  • Publication: May 4, 2010
  • Application: Jun 15, 2006
    US US 45300306 A
  • Priority: Jun 15, 2006
    US US 45300306 A
  • Priority: Apr 28, 2005
    US US 2005/0014444 W
  • Priority: Apr 28, 2005
    US US 11623405 A
  • Priority: Jan 13, 2005
    US US 64317505 P
  • Priority: Apr 28, 2004
    US US 56584604 P

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