Crystal Structure Of Rho-kinase I Kinase Domain Complexes And Binding Pockets Thereof

  • Published: Feb 2, 2010
  • Earliest Priority: Jun 28 2005
  • Family: 2
  • Cited Works: 63
  • Cited by: 0
  • Cites: 6
  • Sequences: 5
  • Additional Info: Cited Works Full text
Data obtained from: EMBL-EBI Pat USPTO Fulltext NCBI GenBank
5 sequences found in this patent (in total)

Filter sequences

Clear
Download sequences in fasta format: 5 peptides

Displaying 5 sequences

SEQ ID NO
Length
Sequence Type
Locations
Declared organism
Determined organism
Occurrence
Tools
SEQ ID NO
1
Length
1,354
Sequence Type
peptide
Locations
Claims, Detailed Description
Declared organism
Homo sapiens
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:4885583
      NP_005397
      1 of 3 hits reported for Homo sapiens.
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,617 bits
    • Similarity
      97.65%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_005397
      100% cov
    • Alignment Length
      1,359 aa
    • CIGAR string
      1210M2NM2NM4NM4N2I3NM3NM3N5DM3NM3N3IN104M mismatches: 28 - insertions: 5 - deletions: 5
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:114672508
      XP_001151982
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,615.5 bits
    • Similarity
      97.65%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_001151982
      100% cov
    • Alignment Length
      1,359 aa
    • CIGAR string
      13MN1196M2NM2NM4NM4N2I3NM3NM3N5DM3NM3N3IN104M mismatches: 29 - insertions: 5 - deletions: 5
  • Callithrix jacchus

    Callithrix jacchus

    • Public DB hit
      GI:296222357
      XP_002757156
      1 of 2 hits reported for Callithrix jacchus.
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,607.4 bits
    • Similarity
      97.35%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_002757156
      100% cov
    • Alignment Length
      1,359 aa
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:109121747
      XP_001091266
      1 of 2 hits reported for Macaca mulatta.
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,607.4 bits
    • Similarity
      97.5%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_001091266
      100% cov
    • Alignment Length
      1,359 aa
  • Oryctolagus cuniculus

    Oryctolagus cuniculus

    • Public DB hit
      GI:126723142
      NP_001075836
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,598.5 bits
    • Similarity
      97.05%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_001075836
      100% cov
    • Alignment Length
      1,357 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:301774504
      XP_002922672
    • Hit length
      1,389 aa
    • E Value
      0E0
    • BLAST Score
      2,579.3 bits
    • Similarity
      97.12%
    • Coverage
      99.93%
    • Alignment (schematic)

      SEQ ID NO 1
      99.93% cov
      XP_002922672
      97.41% cov
    • Alignment Length
      1,356 aa
  • Equus caballus

    Equus caballus

    • Public DB hit
      GI:255652847
      NP_001157457
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,577.4 bits
    • Similarity
      96.98%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_001157457
      100% cov
    • Alignment Length
      1,357 aa
  • Sus scrofa

    Sus scrofa

    • Public DB hit
      GI:335291161
      XP_003356415
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,576.2 bits
    • Similarity
      97.13%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_003356415
      100% cov
    • Alignment Length
      1,357 aa
  • Canis lupus familiaris

    Canis lupus familiaris

    • Public DB hit
      GI:73961936
      XP_537305
    • Hit length
      2,025 aa
    • E Value
      0E0
    • BLAST Score
      2,560.8 bits
    • Similarity
      97.05%
    • Coverage
      99.93%
    • Alignment (schematic)

      SEQ ID NO 1
      99.93% cov
      XP_537305
      66.81% cov
    • Alignment Length
      1,358 aa
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:6677759
      NP_033097
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      2,554.2 bits
    • Similarity
      96.61%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_033097
      100% cov
    • Alignment Length
      1,357 aa
  • Nomascus leucogenys

    Nomascus leucogenys

    • Public DB hit
      GI:332225949
      XP_003262150
    • Hit length
      1,337 aa
    • E Value
      0E0
    • BLAST Score
      2,542.3 bits
    • Similarity
      95.95%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_003262150
      100% cov
    • Alignment Length
      1,359 aa
  • Rattus norvegicus

    Rattus norvegicus

    • Public DB hit
      GI:13592049
      NP_112360
    • Hit length
      1,369 aa
    • E Value
      0E0
    • BLAST Score
      2,521.9 bits
    • Similarity
      95.34%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_112360
      100% cov
    • Alignment Length
      1,372 aa
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
2
Length
4
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
21 times in PatSeqDB
Tools
SEQ ID NO
3
Length
9
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
  • Fowlpox virus

    Fowlpox virus

    • Public DB hit
      GI:9634828
      NP_039121
    • Hit length
      464 aa
    • E Value
      3.7E2
    • BLAST Score
      27.8 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 3
      100% cov
      NP_039121
      1.94% cov
    • Alignment Length
      9 aa
    • CIGAR string
      8MN mismatches: 1 - insertions: 0 - deletions: 0
  • Fowlpox virus isolate HP-438/Munich

    Fowlpox virus isolate HP-438/Munich

    • Public DB hit
      GI:41023443
      CAE52697
    • Hit length
      200 aa
    • E Value
      5.34E2
    • BLAST Score
      26.9 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 3
      100% cov
      CAE52697
      4.5% cov
    • Alignment Length
      9 aa
    • CIGAR string
      8MN mismatches: 1 - insertions: 0 - deletions: 0
Occurrence
10 times in PatSeqDB
Tools
SEQ ID NO
4
Length
400
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Homo sapiens
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:167887698
      ACA06069
      1 of 3 hits reported for Homo sapiens.
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      855.9 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      ACA06069
      29.54% cov
    • Alignment Length
      400 aa
    • CIGAR string
      N107MN172MN86MN31M mismatches: 4 - insertions: 0 - deletions: 0
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:109121747
      XP_001091266
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      854.7 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XP_001091266
      29.54% cov
    • Alignment Length
      400 aa
    • CIGAR string
      N7MN99MN172MN86MN31M mismatches: 5 - insertions: 0 - deletions: 0
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:114672508
      XP_001151982
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      854.4 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XP_001151982
      29.54% cov
    • Alignment Length
      400 aa
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:6677759
      NP_033097
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      854 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      NP_033097
      29.54% cov
    • Alignment Length
      400 aa
  • Sus scrofa

    Sus scrofa

    • Public DB hit
      GI:335291161
      XP_003356415
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      853.2 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XP_003356415
      29.54% cov
    • Alignment Length
      400 aa
  • Equus caballus

    Equus caballus

    • Public DB hit
      GI:255652847
      NP_001157457
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      852.8 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      NP_001157457
      29.54% cov
    • Alignment Length
      400 aa
  • Oryctolagus cuniculus

    Oryctolagus cuniculus

    • Public DB hit
      GI:126723142
      NP_001075836
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      852.8 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      NP_001075836
      29.54% cov
    • Alignment Length
      400 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:301774504
      XP_002922672
    • Hit length
      1,389 aa
    • E Value
      0E0
    • BLAST Score
      852.8 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XP_002922672
      28.8% cov
    • Alignment Length
      400 aa
  • Rattus norvegicus

    Rattus norvegicus

    • Public DB hit
      GI:13592049
      NP_112360
    • Hit length
      1,369 aa
    • E Value
      0E0
    • BLAST Score
      852.4 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      NP_112360
      29.22% cov
    • Alignment Length
      400 aa
  • Callithrix jacchus

    Callithrix jacchus

    • Public DB hit
      GI:296222357
      XP_002757156
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      852.4 bits
    • Similarity
      99.25%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XP_002757156
      29.54% cov
    • Alignment Length
      400 aa
  • Canis lupus familiaris

    Canis lupus familiaris

    • Public DB hit
      GI:73961936
      XP_537305
    • Hit length
      2,025 aa
    • E Value
      0E0
    • BLAST Score
      838.2 bits
    • Similarity
      99%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XP_537305
      19.75% cov
    • Alignment Length
      400 aa
  • Gallus gallus

    Gallus gallus

    • Public DB hit
      GI:313661353
      NP_001186377
    • Hit length
      1,358 aa
    • E Value
      0E0
    • BLAST Score
      833.2 bits
    • Similarity
      98.5%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      NP_001186377
      29.46% cov
    • Alignment Length
      400 aa
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
5
Length
398
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Homo sapiens
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:4885583
      NP_005397
      1 of 4 hits reported for Homo sapiens.
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      853.6 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      NP_005397
      29.32% cov
    • Alignment Length
      397 aa
    • CIGAR string
      1H296MN72MN27M mismatches: 2 - insertions: 0 - deletions: 0
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:114672508
      XP_001151982
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      852 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      XP_001151982
      29.32% cov
    • Alignment Length
      397 aa
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:109121747
      XP_001091266
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      851.7 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      XP_001091266
      29.32% cov
    • Alignment Length
      397 aa
  • Sus scrofa

    Sus scrofa

    • Public DB hit
      GI:335291161
      XP_003356415
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      850.9 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      XP_003356415
      29.32% cov
    • Alignment Length
      397 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:301774504
      XP_002922672
    • Hit length
      1,389 aa
    • E Value
      0E0
    • BLAST Score
      850.9 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      XP_002922672
      28.58% cov
    • Alignment Length
      397 aa
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:6677759
      NP_033097
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      850.9 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      NP_033097
      29.32% cov
    • Alignment Length
      397 aa
  • Rattus norvegicus

    Rattus norvegicus

    • Public DB hit
      GI:13592049
      NP_112360
    • Hit length
      1,369 aa
    • E Value
      0E0
    • BLAST Score
      850.5 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      NP_112360
      29% cov
    • Alignment Length
      397 aa
  • Callithrix jacchus

    Callithrix jacchus

    • Public DB hit
      GI:296222357
      XP_002757156
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      850.5 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      XP_002757156
      29.32% cov
    • Alignment Length
      397 aa
  • Equus caballus

    Equus caballus

    • Public DB hit
      GI:255652847
      NP_001157457
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      850.5 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      NP_001157457
      29.32% cov
    • Alignment Length
      397 aa
  • Oryctolagus cuniculus

    Oryctolagus cuniculus

    • Public DB hit
      GI:126723142
      NP_001075836
    • Hit length
      1,354 aa
    • E Value
      0E0
    • BLAST Score
      850.1 bits
    • Similarity
      99.5%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      NP_001075836
      29.32% cov
    • Alignment Length
      397 aa
  • Canis lupus familiaris

    Canis lupus familiaris

    • Public DB hit
      GI:73961936
      XP_537305
    • Hit length
      2,025 aa
    • E Value
      0E0
    • BLAST Score
      835.9 bits
    • Similarity
      99.24%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      XP_537305
      19.6% cov
    • Alignment Length
      397 aa
  • Gallus gallus

    Gallus gallus

    • Public DB hit
      GI:313661353
      NP_001186377
    • Hit length
      1,358 aa
    • E Value
      0E0
    • BLAST Score
      830.5 bits
    • Similarity
      98.74%
    • Coverage
      99.75%
    • Alignment (schematic)

      SEQ ID NO 5
      99.75% cov
      NP_001186377
      29.23% cov
    • Alignment Length
      397 aa
Occurrence
2 times in PatSeqDB
Tools

Feedback