Dna Cancer Vaccines

Abstract

A plurality of DNA cancer vaccines and their uses in treating cancer are disclosed. Genes encoding Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) recombinant antigens and genes encoding interleukin-12 heterodimer were respectively cloned into eukaryotic expression vectors to express the encoded recombinant proteins in mammalian cells in vivo whereby specific immune responses are evoked and are effective in preventing, attenuating and/or suppressing the growth of a tumor.


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Document History
  • Publication: Oct 20, 2009
  • Application: Feb 24, 2005
    US US 6467205 A
  • Priority: Feb 24, 2005
    US US 6467205 A

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