Map Kinase Integrin-binding Domain

Abstract

Dislosed is the integrin-binding domain of MAP kinase. Interaction between MAP kinase and integrin via this domain activates MAP kinase and initiates cellular activity. Methods of modulating cellular activity by inhibiting direct MAP kinase-integrin binding are provided. These methods have particular use in inhibiting growth of cancer cells.


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Document History
  • Publication: Sep 9, 2008
  • Application: Apr 16, 2004
    US US 45129104 A
  • Priority: Dec 21, 2001
    AU AU 1972/001016 W
  • Priority: Dec 22, 2000
    AU AU PR230500 A

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