Assay Method


The present invention provides a method for the measurement of the activity of a plasminogen activator, such as urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA) in a biological sample using an assay method characterized by the inclusion of an elastase inhibitor in the assay mixture. The invention also provides a diagnostic kit for the measurement of a plasminogen activator using said method and a method of determining the effective therapeutic dose of a plasminogen activator inhibitor using said method. Also provided is a method of preparing a pharmaceutical composition.

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Document History
  • Publication: May 16, 2006
  • Application: May 17, 2002
    US US 13036802 A
  • Priority: Dec 5, 2000
    GB GB 0004647 W
  • Priority: Dec 8, 1999
    GB GB 9928882 A

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