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(i) a vector encoding and capable of expressing a nitroreductase enzyme in a tumour cell, or a tumour-directed antibody linked to a nitroreductase enzyme; and
(ii) a compound of formula (Ia):wherein Y is a lower alkyl group having 1 to 6 carbon atoms and being substituted with one or more of the following groups: methylcarboxy, imidazolyl and morpholinyl."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["A method of treating neoplastic disease which comprises administering to a patient in need of such treatment a therapeutically effective amount of a two component system which comprises:
(i) a vector encoding and capable of expressing a nitroreductase enzyme in a tumour cell, or a tumour-directed antibody linked to a nitroreductase enzyme; and
(ii) a compound of formula (Ia):wherein Y is a lower alkyl group having 1 to 6 carbon atoms and being substituted with one or more of the following groups: methylcarboxy, imidazolyl and morpholinyl."],"number":8,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}