Therapeutic Uses Of Il-1 Receptor Antagonist


The present invention provides novel therapeutic methods of administering an amount of IL-1Ra to treat IL-18 related disorders. Specifically, the method involves treating IL-18 related disorders such as liver injury, hepatis, hemophagocytic lymphohistiocytosis, multiple sclerosis, tumors, cytotoxicity resulting from antitumor therapy, or other autoimmune disorders with a therapeutically effective amount of IL-1ra, and optionally measuring IFN-gamma and IL-18 activity from human samples.

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Document History
  • Publication: Dec 24, 2002
  • Application: May 22, 2000
    US US 57675500 A
  • Priority: May 22, 2000
    US US 57675500 A

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