Method To Determine Inhibition Of Pak3 Activation Of Raf-1


A method is provided to determine the ability of a test compound to alter PAK activation of Raf-1 comprising: (a) contacting a polypeptide comprising the catalytic domain of a PAK with the test compound in the presence of Raf-1; and (b) measuring the extent of activation of Raf-1.

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Document History
  • Publication: May 7, 2002
  • Application: Sep 30, 1998
    US US 16350798 A
  • Priority: Sep 30, 1998
    US US 16350798 A

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