Jagged1 As A Marker And Therapeutic Target For Breast Cancer Bone Metastasis

Abstract

A method of treating Jagged1 induced bone metastasis is provided. A method of analyzing patients with tumors insensitive to RANK targeting treatments, but may respond to Jagged1 or Notch targeting therapies is provided. A method of treating patients with Jagged1 induced bone metastasis is provided. A method of predicting the therapeutic of treating a cancer patient with bone metastasis is provided. A kit for treating patients with Jagged1 induced bone metastasis is provided. A kit for predicting the therapeutic outcome of treating a cancer patient with bone metastasis using RANKL inhibitors is provided.


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Document History
  • Publication: Nov 21, 2013
  • Application: Feb 2, 2012
    US US 201213982688 A
  • Priority: Feb 2, 2012
    US US 201213982688 A
  • Priority: Feb 2, 2012
    US US 2012/0023655 W
  • Priority: Feb 2, 2011
    US US 201161438826 P

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