Doc Type: Patent Application
Abstract

Methods for producing engineered induced pluripotent stem (iPS) cells are provided comprising introducing a first nucleic acid into somatic cells for integration into their genome and reprogramming the cells to produce engineered iPS cells having the nucleic acid integrated into their genome. For example, in certain aspects the cells are reprogrammed by introduction of a genetic element that expresses one or more reprogramming factor and culturing of the cells under conditions sufficient to produce reprogrammed cells.


Claims
CPC Classifications
Download PDF
Document Preview
Document History
  • Publication: Feb 14, 2013
  • Application: Jul 11, 2012
    US US 201213546365 A
  • Priority: Jul 11, 2012
    US US 201213546365 A
  • Priority: Jul 11, 2011
    US US 201161506314 P

Sign in to the Lens