{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_2012_0289760_A1","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"093-964-759-836-031"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11697,"type":"PATENT","title":"Oregon Health and Science University - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":2948,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8352,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
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Search Applicants and Owners separately: oregon uni*
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Select all patents in the collection and expand by simple families.
Add to collection. Total patents: 2661
administering to the subject, by intraperitoneal or intravenous administration, a recombinant, replication-deficient cytomegalovirus comprising a heterologous nucleic acid encoding the antigen, whereby viral latency is established in the subject, thereby generating the repeatedly stimulated immune response against the antigen."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the repeatedly stimulated immune response comprises a CD8+ T cell immune response."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the heterologous antigen comprises a bacterial, fungal, viral, or tumor-derived polypeptide."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3, wherein the tumor-derived polypeptide is a cancer antigen."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the recombinant replication-deficient cytomegalovirus comprises an inactivated gB, gD, gH, or gL glycoprotein gene."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 5, wherein the inactivated gene encodes the gL glycoprotein."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 6, wherein the gene encoding the gL glycoprotein is inactivated by a knock out mutation."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the nucleic acid encoding the antigen is operably linked to a constitutive promoter."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the nucleic acid encoding the antigen is operably linked to an inducible promoter."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the recombinant replication-deficient cytomegalovirus is a murine cytomegalovirus."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein the recombinant replication-deficient cytomegalovirus is a human cytomegalovirus."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 11, wherein the human cytomegalovirus is selected from the group consisting of AD169, Davis, Toledo, and Towne."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["A method of treating a subject who has been diagnosed with a cancer comprising:\n
administering to the subject a chemotherapeutic agent, or a immunologic anti-cancer agent, or both; and\n
administering to the subject, by intraperitoneal or intravenous administration, a recombinant, replication-deficient cytomegalovirus comprising a heterologous nucleic acid encoding a heterologous antigen derived from the cancer, whereby viral latency is established in the subject, thereby generating repeatedly stimulated immunity against the cancer."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 13, wherein the repeatedly stimulated immunity comprises a CD8+ T cell immune response."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 14, wherein the recombinant replication-deficient cytomegalovirus comprises an inactivated gB, gD, gH, and gL glycoprotein gene."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 15, wherein the inactivated gene encodes a gL glycoprotein."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 16, wherein the gene encoding the gL glycoprotein is inactivated by a knock out mutation."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 13, wherein the recombinant replication-deficient cytomegalovirus is a human cytomegalovirus."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 18, wherein the human cytomegalovirus is selected from the group consisting of AD169, Davis, Toledo, and Towne."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 13, further comprising administering radiation therapy to the subject."],"number":20,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}