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Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
the β subunit includes an amino acid sequence set forth in SEQ ID NO: 3 or an amino acid sequence that is different from the amino acid sequence set forth in SEQ ID NO: 3 only in a part that does not substantially affect a function of the proteasome β subunit."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The expression construct according to claim 1, wherein the nucleic acid sequence includes a DNA sequence set forth in SEQ ID NO: 2 and/or a DNA sequence set forth in SEQ ID NO: 4."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The expression construct according to claim 1, wherein the archaea belongs to the Methanosarcina genus."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The expression construct according to claim 1, wherein the archaea is Methanosarcina mazei. "],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The expression construct according to claim 1, wherein the promoter for a eukaryotic cell is a promoter for a mammalian."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The expression construct according to claim 1, wherein the aggregative protein is a protein selected from the group consisting of mutant superoxide dismutase 1, an androgen receptor having an abnormally extended polyglutamine chain, α-synuclein, and tau."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["A method of inhibiting an aggregative protein from forming an aggregate in a target eukaryotic cell, the method comprising introducing the expression construct according to claim 1 into the target eukaryotic cell."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["A method of inhibiting an aggregative protein from forming an aggregate in a target eukaryotic cell, the method comprising forcedly expressing archaeal proteasome α subunit and β subunit in the target eukaryotic cell."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 10, wherein the archaea belongs to the Methanosarcina genus."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 10, wherein the archaea is Methanosarcina mazei. "],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 9, wherein the target eukaryotic cell is a human cell."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The method described in claim 9, wherein the target eukaryotic cell is an isolated human cell."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["The method described in claim 9, wherein the target eukaryotic cell is a non-human mammalian cell."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["A use of a proteasome of archaea to prepare an expression construct for degrading an aggregative protein or to inhibit an aggregative protein from forming an aggregate in a target eukaryotic cell."],"number":16,"annotation":false,"claim":true,"title":false},{"lines":["The expression construct according to claim 2, wherein the archaea belongs to the Methanosarcina genus."],"number":17,"annotation":false,"claim":true,"title":false},{"lines":["The expression construct according to claim 2, wherein the archaea is Methanosarcina mazei. "],"number":18,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 10, wherein the target eukaryotic cell is a human cell."],"number":19,"annotation":false,"claim":true,"title":false},{"lines":["The method described in claim 10, wherein the target eukaryotic cell is an isolated human cell."],"number":20,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}