Methods For Selective Targeting

Abstract

A selective targeting method is disclosed comprising contacting a library of ligands, particularly a peptide library, with an anti-target to allow the ligands to bind to the anti-target; separating the non-binding ligands from the anti-target bound ligands, contacting the non-binding anti-target ligands with a target allowing the unbound ligands to bind with the target to form a target-bound ligand complex; separating the target-bound ligand complex from ligands which do not bind to the target, and identifying the target-bound ligands on the target-bound ligand complex wherein the target-bound ligands have a KD in the range of about 10-7 to 10-10 M. Additionally claimed are the ligands identified according to the method.


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Document History
  • Publication: Apr 9, 2009
  • Application: Apr 8, 2008
    US US 9963208 A
  • Priority: Apr 8, 2008
    US US 9963208 A
  • Priority: Oct 19, 2004
    US US 96873204 A
  • Priority: Apr 11, 2001
    US US 83272301 A
  • Priority: Apr 14, 2000
    US US 19725900 P

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