Abstract

Provided is a compound that comprises the structure: (I) where SIG is a signaling molecule and R3 is a formyl, a succinyl, a methyl succinyl, or a myristoyl. Also provided is a kit is provided that comprises the above compound, with instructions for determining the presence of the enzyme. Additionally, a method is provided for determining whether a sample has an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an µ-amino of a lysine. Also provided is a method of determining whether a molecule inhibits an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an µ-amino of a lysine.


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Document History
  • Publication: Jun 4, 2019
  • Application: Apr 3, 2018
    US US 201815944336 A
  • Priority: Apr 3, 2018
    US US 201815944336 A
  • Priority: Mar 21, 2017
    US US 201715464966 A
  • Priority: Jan 13, 2011
    US US 93069311 A

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