Murine Anti-ny-eso-1 T Cell Receptors


The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for NY-ESO-1. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a mammal and a method of treating or preventing cancer in a mammal using the inventive TCRs or related materials.

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Document History
  • Publication: Oct 2, 2018
  • Application: Sep 16, 2016
    US US 201615267285 A
  • Priority: Sep 16, 2016
    US US 201615267285 A
  • Priority: Nov 18, 2014
    US US 201414401893 A
  • Priority: May 22, 2013
    US US 2013/0042162 W
  • Priority: May 22, 2012
    US US 201261650020 P

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