Mirna-489 In Treatment Of Breast Cancer

Abstract

Breast cancer treatment methods and materials incorporating microRNA-489 are described. The methods and materials have been developed from identification of a double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis. The methods and materials may be particularly beneficial in treatment and diagnosis of HER2 positive breast cancers.


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Document History
  • Publication: Aug 21, 2018
  • Application: Jan 20, 2017
    US US 201715411314 A
  • Priority: Jan 20, 2017
    US US 201715411314 A
  • Priority: Jan 21, 2016
    US US 201662281338 P

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