Methods Of Preventing Neurodegeneration Of Association Cortex In A Mammal

Abstract

The present invention provides methods of preventing and/or reducing risk of neurodegeneration of association cortex, and/or inhibiting or reversing formation of phosphorylated tau or COXIV in the prefrontal cortex of a mammal in need thereof. In certain embodiments, the method comprises administering to the mammal a therapeutically effective amount of an α2A-adrenergic receptor agonist.


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Document History
  • Publication: Jul 17, 2018
  • Application: Dec 2, 2015
    US US 201515532420 A
  • Priority: Dec 2, 2015
    US US 201515532420 A
  • Priority: Dec 2, 2015
    US US 2015/0063428 W
  • Priority: Dec 2, 2014
    US US 201462086363 P

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