Recombinant Bone Morphogenetic Protein

  • Published: May 7, 2003
  • Family: 19
  • Sequences: 30
  • Additional Info: Sequence
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Abstract

PROBLEM TO BE SOLVED: To provide a method for producing a recombinant homodimeric BMP protein useful in the field of treating bone defects, healing bone injury and in wound healing in general, and to provide the recombinant homodimer and a composition including the same. SOLUTION: This recombinant BMP-2 homodimeric protein produced in E. coli and having bone stimulating activity is provided. The method for producing the homodimeric BMP-2 protein comprises culturing an E. coli host cell and then isolating and purifying the homodimeric BMP-2 protein from the resultant culture medium.


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Document History
  • Publication: May 7, 2003
  • Application: Jul 22, 2002
    JP 2002212805 A
  • Priority: Apr 7, 1992
    US US 86469292 A
  • Priority: Nov 4, 1991
    US US 78749691 A

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