Modulation Of Apolipoprotein Ciii (apociii) Expression

  • Published: Aug 8, 2018
  • Earliest Priority: Apr 27 2011
  • Family: 43
  • Cited Works: 116
  • Cited by: 0
  • Cites: 40
  • Sequences: 5
  • Additional Info: Cited Works Sequence
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Abstract

Provided herein are methods, compounds, and compositions for reducing expression of ApoCIII mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for increasing HDL levels and/or improving the ratio of TG to HDL and reducing plasma lipids and plasma glucose in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disorder, or a symptom thereof.


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Document History
  • Publication: Aug 8, 2018
  • Application: Apr 27, 2012
    EP EP 18155337 A
  • Priority: Apr 27, 2012
    EP EP 12776385 A
  • Priority: Apr 27, 2012
    US US 2012/0035694 W
  • Priority: Feb 3, 2012
    US US 201261595009 P
  • Priority: Apr 27, 2011
    US US 201161479817 P

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